Emily got a Nano for her birthday. Here are the odd things I noticed that, I'd guess, most wouldn't.
1. When you export all contacts from OS X Address book, a single file is created, not a set of .vcf files. Interestingly the Nano can handle this file. This is the easiest way to dump a bunch of contact data manually into the Nano. I'll experiment with dumping more than one of these. (iTunes mediation of syncing with Address Book is messed up when multiple users share the same music library.)
2. Gordon's Tech: iTunes and iPod integration and oddities mentions sharing a cable with an older iPod and some oddities of iTunes integration. Alas, the kb is wrong. The 3G firewire iPod will not sync using the cable that comes with the Nano.
More to come ...