Document scanning w/ OS X has been difficult. This Macintouch poster suggests a solution:
It would appear that MindWrap's ScanTango would be an excellent solution. It claims to work with Fujitsu Scanners. On the basis of their claims and an earlier posting here by Randy Singer, I am purchasing a Fujitsu fi-5110EOX [$432.99 @ Amazon] from MacConnection and giving it a try.